Team
Christoph Saffer

Christoph Saffer

Guest scientist, Post-doctoral researcher

Contact & more info

Curriculum vitae

Main Research Areas

Mathematical modeling of microbial dynamics and host-pathogen interactions
Computational stochastic simulations of fungal infection scenarios
Mechanisms of the innate immunity in the lung

Professional Career

since 2024 Research associate in the group Applied Systems Biology at the Leibniz-HKI Jena
2020 – 2024 PhD student in the group Applied Systems Biology at the Leibniz-HKI Jena
2019 M.Sc. in Computer Science at the Friedrich Schiller University Jena
2019 Semester abroad at the University of Valencia
2017 B.Sc. in Mathematics at the Friedrich Schiller University Jena
2016/17 Semester abroad at the Charles University Prague

Publications

2025-11-16

Mechanistic Insights into the Role of Extracellular Vesicles at the Bacterial−Host Interface

Miriana Battista, Christoph Saffer, Marc Thilo Figge and Cláudia Vilhena*

ACS Infectious Diseases

Open Access PDF

2024-11-10

Spatiotemporal modeling quantifies cellular contributions to uptake of Aspergillus fumigatus in the human lung

Saffer C, Timme S, Ortiz SC, Bertuzzi M, Figge MT

Communications Biology

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2024-07-23

Unique target binding by the C-terminal Region of FHR1 provides a new perception of aHUS Pathology

Luce Perie, Selina Stippa, Christoph Saffer, Andrea Hartmann , Mathias Mörgelin, Svante L. H. Zipfel, Marc Thilo Figge, Thorsten Wiech, Christine Skerka, and Peter F. Zipfel

Front. Hematol.

Open Access

2023-04-10

Surrogate infection model predicts optimal alveolar macrophage number for clearance of Aspergillus fumigatus infections

Saffer C, Timme S, Rudolph P, Figge MT#

PJ Syst Biol Appl.

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2022-04-01

Invasive aspergillosis-on-chip: A quantitative treatment study of human Aspergillus fumigatus infection

T N M Hoang, Z Cseresnyés, S Hartung, M Blickensdorf, C Saffer, K Rennert, A S Mosig, M von Lilienfeld-Toal #, M T Figge#

Biomaterials

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