Applied Systems Biology - Leibniz-HKI Jena

Publication data

Here is where we host the publication data: asbdata.hki-jena.de

2026-11-12

Tyrosine-containing fungal HscA orthologues contribute to host membrane damage

Lei-Jie Jia¹#, Freddy A. Bernal² , Jeany Söhnlein³ ⁴, Shivam Chaudhary⁵, Johannes Sonnberger⁶, Isabel Heineking¹ ⁴, Muhammad Rafiq¹ , Zoltán Cseresnyés⁷, Franziska Kage¹ ⁴, Franziska Schmidt³, Rasha Zaher³ ⁴, Dominik Schmidt¹, Peter Hortschansky³, Xue-Min Gong⁸, Marc Thilo Figge⁴ ⁷ ⁹, Bernhard Hube⁴ ⁶ ⁹, Jan Schirawski⁵, Axel A. Brakhage³ ⁴ ⁹#

Nature Communications

2026-11-05

AI-powered image analysis of fungal infections: A review of advances in research and diagnostics

Carl-Magnus Svensson, Marc Thilo Figge#

Therapeutic Advances in Infectious Disease

Open Access PDF

2026-10-30

Dectin-1-dependent phagocytosis of Aspergillus fumigatus triggers robust leukotriene B4 formation in human pro-inflammatory macrophages

Kerstin Günther, Tom Schöne, Zoltan Cseresnyés, Corissa Visser, Vivien Nischang, Jethro L. Hemmann, Slavica Janevska, Francisco Páez Larios, Zahraa Abboud, Dalia Sheta, Thorsten Heinekamp, Olaf Kniemeyer, Christian Eggeling, Andreas Beilhack, Axel A. Brakhage, Marc Thilo Figge, Oliver Werz#, Paul M. Jordan#

Cell Reports

2026-08-29

Host-to-Pathogen Transfer of Neutrophil Components via Extracellular Vesicles Shields Candida albicans From Immune Attack in Human Blood

Jennifer J. Patitz, Natalie E. Nieuwenhuizen, Anastasia Solomatina, Yann Bachelot, Thomas Krüger, Carl-Magnus Svensson, Stephanie Hoeppener, Ann-Kathrin Zimmermann, Matthew G. Blango, Ronny Martin, Olaf Kniemeyer, Theresa Lange, Axel A. Brakhage, Marc Thilo Figge, Oliver Kurzai#, Kerstin Hünniger-Ast

Journal of Extracellular Vesicles

OpenAccess PDF PubMed

2026-07-28

Assessing the proinflammatory potential of sterile fecal microbiome filtrate from ulcerative colitis patients using an intestine-on-chip platform and automated image analysis

Schaal T*, Akbarimoghaddam P*, Wegner VD, Steube A, Gardey E, Feile A, Hassan MIA, Cseresnyés Z, Stallmach A, Mosig AS, Figge MT#, Stallhofer J#

Gut Microbes 18(1)

OpenAccess PubMed PDF

2026-07-24

Reconstructing host-pathogen interactions: analysis of the intercellular network of macrophages and other immune cells within an Aspergillosis-on-chip model.

Simranpreet Kaur*, Anna Katharina Renner*, Pauline Porschitz*, Franziska Schmidt*, Svenja Grau, Hannah Afolayan, Stanislaw Schmidt, Thomas Lehrnbecher-Lanzeni, Hubertus Haas, Axel A. Brakhage, Marc Thilo Figge, Marie von Lilienfeld-Toal, Zoltan Cseresnyés*, Susann Hartung*, Susanne Jahreis*

microLife