2025-09-15

Selective activation of dynamics in kinetically frozen supramolecular polymer bottlebrush assemblies

Hans F. Ulrich, Tobias Klein, Ziliang Zhao, Zoltán Cseresnyés, Pablo Carravilla, Ruman Gerst, Alina Kasberg, Frederic P. Scharfenberg, Marc Thilo Figge, Christian Eggeling, Johannes C. Brendel

Small

2025-03-06

Convergent evolution of a fungal effector enabling phagosome membrane penetration

Lei-Jie Jia, Freddy Alexander Bernal, Jeany Söhnlein, Johannes Sonnberger, Isabel Heineking, Muhammad Rafiq, Zoltán Cseresnyés, Franziska Kage, Franziska Schmidt, Rasha Zaher, Peter Hortschansky, Shivam Chaudhary, Xuemin Gong, Jan Schirawski, Marc Thilo Figge, Bernhard Hube, Axel A. Brakhage

bioRxiv

2025-03-01

Intuitive workflows for automated image analysis - JIPipe as an open-source tool for FAIR image analysis.

Ruman Gerst, Zoltán Cseresnyés, Figge#

Microscopy and Analysis

2025-02-19

Intuitive Abläufe für die automatisierte Bildanalyse. JIPipe als quelloffene Softwarelösung für FAIRe Bildanalyse

Gerst R, Cseresnyés Z, Figge MT#

Wiley Analytical Science

2024-12-05

The proteomic response of Aspergillus fumigatus to amphotericin B (AmB) reveals the involvement of the RTA-like protein RtaA in AmB resistance

Ammar Abou-Kandil, Sophie Tröger-Görler, Annica Pschibul, Thomas Krüger, Maira Rosin, Franziska Schmidt, Parastoo Akbarimoghaddam, Arjun Sarkar, Zoltán Cseresnyés, Yana Shadkchan, Thorsten Heinekamp, Markus H Gräler, Amelia E Barber, Grit Walther, Marc Thilo Figge, Axel A Brakhage, Nir Osherov, Olaf Kniemeyer

MicroLife

2024-11-06

Tracking the uptake of labelled host-derived extracellular vesicles by the human fungal pathogen Aspergillus fumigatus

Visser C, Rivieccio F, Krüger T, Schmidt F, Cseresnyés Z, Rohde M, Figge MT, Kniemeyer O,Blango MG*, Brakhage AA*

microLife

2024-09-13

Aspergillus fumigatus-derived gliotoxin impacts innate immune cell activation through modulating lipid mediator production in macrophages

Günther K, Nischang V, Cseresnyés Z, Krüger T, Sheta D, Abboud Z, Heinekamp T, Werner M, Kniemeyer O, Beilhack A, Figge MT, Brakhage AA, Werz O#, Jordan PM#

Immunology

2024-05-23

Selective Uptake Into Inflamed Human Intestinal Tissue and Immune Cell Targeting by Wormlike Polymer Micelles

Elena Gardey, Zoltan Cseresnyes, Fabian H. Sobotta, Juliane Eberhardt, Drilon Haziri, Philip C. Grunert, Maren T. Kuchenbrod, Franka V. Gruschwitz, Stephanie Hoeppener, Michael Schumann, Nikolaus Gaßler, Marc T. Figge, Andreas Stallmach, Johannes C. Brendel

Small

2024-02-21

The spatial organization of sphingofungin biosynthesis in Aspergillus fumigatus and its cross-interaction with sphingolipid metabolism

Jojić K*, Gherlone F*, Cseresnyés Z, Bissell AU, Hoefgen S, Hoffmann S, Huang Y, Janevska S, Figge MT, Valiante V

Molecular and Cellular Biology

2023-09-22

Hydrophilic cryogels as potential 3D cell culture materials: Synthesis and characterization of 2-(methacrylamido) glucopyranose-based polymer scaffolds

Behrendt F, Pretzel D, Cseresnyés Z, Kleinsteuber M, Wloka T, Radosa L, Figge MT, Gottschaldt M, Brakhage AA, Schubert US#

Journal of Polymer Science

2023-05-27

Evaluation of reproducible cryogel preparation based on automated image analysis using deep learning

Behrendt F*, Cseresnyés Z*, Gerst R, Gottschaldt M, Figge MT#, Schubert US#

J Biomed Mater Res A

2023-05-09

Guided-deconvolution for correlative light and electron microscopy

Ma F, Kaufmann R, Sedzicki J, Cseresnyés Z, Dehio C, Hoeppener S, Figge MT, Heintzmann R

PLoS One

2023-03-08

Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway

Jia LJ, Rafiq M, Radosa L, Hortschansky P, Cunha C, Cseresnyés Z, Krüger T, Schmidt F, Heinekamp T, Straßburger M, Loeffler B, Doenst T, Lacerda JF, Campos A, Figge MT, Carvalho A, Kniemeyer O, Brakhage AA

Cell Host & Microbe

2023-01-31

The lipid raft-associated protein stomatin is required for accumulation of dectin-1 in the phagosomal membrane and for full activity of macrophages against Aspergillus fumigatus

Goldmann M, Schmidt F, Cseresnyés Z, Orasch T, Jahreis S, Hartung S, Figge MT, von Lilienfeld-Toal M, Heinekamp T, Brakhage AA

mSphere

2023-01-21

Tuning the corona-core ratio of polyplex micelles for selective oligonucleotide delivery to hepatocytes or hepatic immune cells

Foo WL, Cseresnyés Z, Rössel C, Teng Y, Ramoji A, Chi M, Hauswald W, Huschke S, Hoeppener S, Popp J, Schacher FH, Sierka M, Figge MT, Press AT#, Bauer M#

Biomaterials

2023-01-20

Polymer-based particles against pathogenic fungi: A non-uptake delivery of compounds

Orasch T*, Gangapurwala G*, Vollrath A, González K, Alex J, De San Luis A, Weber C, Hoeppener S, Cseresnyés Z, Figge MT, Guerrero-Sanchez C, Schubert US#, Brakhage AA#

Biomaterials Advances

2023-01-10

JIPipe: Visual batch processing for ImageJ

Gerst R*, Cseresnyés Z*, Figge MT#

Nature Methods

2022-12-08

Targeting of phagolysosomes containing conidia of the human pathogenic fungus Aspergillus fumigatus with polymeric particles

González K*, Gangapurwala G*, Alex J*, Vollrath A, Cseresnyés Z, Weber C, Czaplewska JA, Hoeppener S, Svensson CM, Orasch T, Heinekamp T, Guerrero-Sánchez C, Figge MT, Schubert US, Brakhage AA

Applied Microbial and Cell Physiology

2022-10-19

Analysis of HDACi-coupled Nanoparticles: Opportunities and challenges

Kühne M, Hofmann S, Lindemann H, Cseresnyés Z, Dzierza A, Schröder D, Godmann M, Koschella A, Eggeling C, Fischer D, Figge MT, Heinze T, Heinzel T

Methods in Molecular Biology

2022-08-05

Toxin-producing endosymbionts shield pathogenic fungus against micropredators

Richter I, Radosa S, Cseresnyés Z, Ferling I, Büttner H, Niehs SP, Gerst R, Scherlach K, Figge MT, Hillmann F, Hertweck C

mBio

2022-08-01

Human macrophage polarization determines bacterial persistence of Staphylococcus aureus in a liver-on-chip-based infection model

Fatina Siwczak, Zoltan Cseresnyes, Mohamed I.Abdelwahab Hassan, Kehinde Oluwasegun Aina, Swen Carlstedt, Anke Sigmund, Marko Groger, Bas G.J. Surewaard, Oliver Werz, Marc Thilo Figge, Lorena Tuchscherr, Bettina Loffler, Alexander S. Mosig#

Biomaterials

2022-06-22

Spatial quantification of clinical biomarker pharmacokinetics through deep learning-based segmentation and signal-oriented analysis of MSOT data

Hoffmann B*, Gerst R*, Cseresnyés Z, Foo W, Sommerfeld O, Press AT, Bauer M, Figge MT

Photoacoustics

2022-04-01

Invasive aspergillosis-on-chip: A quantitative treatment study of human Aspergillus fumigatus infection

T N M Hoang, Z Cseresnyés, S Hartung, M Blickensdorf, C Saffer, K Rennert, A S Mosig, M von Lilienfeld-Toal #, M T Figge#

Biomaterials

2021-09-09

Bacterial endosymbionts protect beneficial soil fungus from nematode attack

Hannah Büttner*, Sarah P Niehs*, Koen Vandelannoote, Zoltán Cseresnyés, Benjamin Dose, Ingrid Richter, Ruman Gerst, Marc Thilo Figge, Timothy P Stinear , Sacha J Pidot, Christian Hertweck#

PNAS

2021-09-02

Targeted delivery of a phosphoinositide 3‐kinase γ inhibitor to restore organ function in sepsis

Adrian T Press*, Petra Babic, Bianca Hoffmann, Tina Müller, Wanling Foo, Walter Hauswald, Jovana Benecke, Martina Beretta, Zoltán Cseresnyés, Stephanie Hoeppener, Ivo Nischang, Sina M Coldewey, Markus H Gräler, Reinhard Bauer, Falk Gonnert, Nikolaus Gaßler, Reinhard Wetzker, Marc Thilo Figge, Ulrich S Schubert, Michael Bauer#

EMBO Mol Med

2021-07-16

Stealth Effect of Short Polyoxazolines in Graft Copolymers: Minor Changes of Backbone End Group Determine Liver Cell-Type Specificity

Irina Muljajew*, Sophie Huschke*, Anuradha Ramoji, Zoltán Cseresnyés, Stephanie Hoeppener, Ivo Nischang, Wanling Foo, Jürgen Popp, Marc Thilo Figge, Christine Weber, Michael Bauer, Ulrich S Schubert#, Adrian T Press#

ACS Nano

2021-04-03

Expression Patterns in Reductive Iron Assimilation and Functional Consequences during Phagocytosis of Lichtheimia corymbifera, an Emerging Cause of Mucormycosis

Felicia Adelina Stanford, Nina Matthies, Zoltán Cseresnyés, Marc Thilo Figge, Mohamed I Abdelwahab Hassan, Kerstin Voigt

Journal of Fungi

2021-01-10

Biocompatible sulfated valproic acid-coupled polysaccharide-based nanocarriers with HDAC inhibitory activit

Marie Kühne, Henry Lindemann, Christian Grune, Daniel Schröder, Zoltán Cseresnyés, Maren Godmann, Andreas Koschella, Marc Thilo Figge, Christian Eggeling, Dagmar Fischer, Thomas Heinze#, Thorsten Heinzel#

Journal of Controlled Release

2020-08-18

Flotillin-Dependent Membrane Microdomains Are Required for Functional Phagolysosomes against Fungal Infections

Franziska Schmidt*, Andreas Thywißen, Marie Goldmann, Cristina Cunha, Zoltán Cseresnyés, Hella Schmidt, Muhammad Rafiq, Silvia Galiani, Markus H Gräler, Georgios Chamilos, João F Lacerda, António Campos Jr, Christian Eggeling, Marc Thilo Figge, Thorsten Heinekamp, Scott G Filler, Agostinho Carvalho, Axel A Brakhage#

Cell Reports

2020-06-24

Functional surface proteomic profiling reveals the host heat-shock protein A8 as a mediator of Lichtheimia corymbifera recognition by murine alveolar macrophages

Mohamed I Abdelwahab Hassan*, Janis M Kruse, Thomas Krüger, Hans-Martin Dahse, Zoltán Cseresnyés, Matthew G Blango, Hortense Slevogt, Franziska Hörhold, Volker Ast, Rainer König, Marc Thilo Figge, Olaf Kniemeyer, Axel A Brakhage, Kerstin Voigt#

Environmental Microbiology

2020-06-05

Quantitative Impact of Cell Membrane Fluorescence Labeling on Phagocytosis Measurements in Confrontation Assays

Zoltan Cseresnyes*, Mohamed I Abdelwahab Hassan*, Hans-Martin Dahse, Kerstin Voigt, Marc Thilo Figge

Frontiers in Microbiology

2020-04-30

The Transcription Factor Stp2 Is Important for Candida albicans Biofilm Establishment and Sustainability

Bettina Böttcher, Bianca Hoffmann, Enrico Garbe, Tobias Weise, Zoltán Cseresnyés, Philipp Brandt, Stefanie Dietrich, Dominik Driesch, Marc Thilo Figge, Slavena Vylkova

Frontiers in Microbiology

2020-04-28

The Amyloid-beta rich CNS environment alters myeloid cell functionality independent of their origin

Natalia Drost*, Judith Houtman*, Zoltán Cseresnyés, Raluca Niesner, Jan-Leo Rinnenthal, Kelly R Miller, Stefan Prokop#, Frank L Heppner#

Scientific Reports

2020-04-16

Staphylococcus aureus Lung Infection Results in Down-Regulation of Surfactant Protein-A Mainly Caused by Pro-Inflammatory Macrophages

Elisabeth Schicke, Zoltán Cseresnyés, Knut Rennert, Vanessa Vau, Karoline Frieda Haupt, Franziska Hornung, Sandor Nietzsche, Fatina Swiczak, Michaela Schmidtke, Brigitte Glück, Mirijam Koch, Michael Schacke, Regine Heller, Alexander S Mosig, Marc Thilo Figge, Christina Ehrhardt, Bettina Löffler, Stefanie Deinhardt-Emmer

Microorganisms

2020-04-14

Human Neutrophils Produce Antifungal Extracellular Vesicles against Aspergillus fumigatus

Iordana A Shopova, Ivan Belyaev, Prasad Dasari, Susanne Jahreis, Maria C Stroe, Zoltán Cseresnyés, Ann-Kathrin Zimmermann, Anna Medyukhina, Carl-Magnus Svensson, Thomas Krüger, Viktòria Szeifert, Sandor Nietzsche, Theresia Conrad, Matthew G Blango, Olaf Kniemeyer, Marie von Lilienfeld-Toal, Peter F Zipfel, Erzsébet Ligeti, Marc Thilo Figge, Axel A Brakhage

mBio

2020-04-08

Dynamic spherical harmonics approach for shape classification of migrating cells

Anna Medyukhina*, Marco Blickensdorf*, Zoltán Cseresnyés, Nora Ruef, Jens V Stein, Marc Thilo Figge#

Scientific Reports

2020-02-19

Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model

Stefanie Deinhardt-Emmer, Knut Rennert, Elisabeth Schicke, Zoltán Cseresnyés, Maximilian Windolph, Sandor Nietzsche, Regine Heller, Fatina Siwczak, Karoline Frieda Haupt, Swen Carlstedt, Michael Schacke, Marc Thilo Figge, Christina Ehrhardt, Bettina Löffler, Alexander S Mosig

Biofabricatio

2019-11-01

A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies

Michelle Maurer, Mark S Gresnigt, Antonia Last, Tony Wollny, Florian Berlinghof, Rebecca Pospich, Zoltan Cseresnyes, Anna Medyukhina, Katja Graf, Marko Gröger, Martin Raasch, Fatina Siwczak, Sandor Nietzsche, Ilse D Jacobsen, Marc Thilo Figge, Bernhard Hube, Otmar Huber, Alexander S Mosig#

Biomaterials

2019-07-22

The geographical region of origin determines the phagocytic vulnerability of Lichtheimia strains

Mohamed I Abdelwahab Hassan*, Zoltan Cseresnyes*, Naim Al-Zaben, Hans-Martin Dahse, Rafael J Vilela de Oliveira, Grit Walther, Kerstin Voigt#, Marc Thilo Figge#

Environmental Microbiology

2018-10-28

Morphology-Based Distinction Between Healthy and Pathological Cells Utilizing Fourier Transforms and Self-Organizing Maps

Fabian L Kriegel*, Ralf Köhler, Jannike Bayat-Sarmadi, Simon Bayerl, Anja E Hauser, Raluca Niesner, Andreas Luch, Zoltan Cseresnyes#

Journal of Visualized Experiments

2018-08-03

Aspf2 From Aspergillus fumigatus Recruits Human Immune Regulators for Immune Evasion and Cell Damage

Prasad Dasari, Iordana A Shopova, Maria Stroe, Dirk Wartenberg, Hans Martin-Dahse, Niklas Beyersdorf, Peter Hortschansky, Stefanie Dietrich, Zoltán Cseresnyés, Marc Thilo Figge, Martin Westermann, Christine Skerka, Axel A Brakhage, Peter F Zipfel

Frontiers in Immunology

2017-10-27

Cell shape characterization and classification with discrete Fourier transforms and self-organizing maps

Fabian L Kriegel*, Ralf Köhler, Jannike Bayat-Sarmadi, Simon Bayerl, Anja E Hauser, Raluca Niesner, Andreas Luch, Zoltan Cseresnyes#

Cytometry A

2017-09-15

Hessian-based quantitative image analysis of host-pathogen confrontation assays

Zoltan Cseresnyes, Kaswara Kraibooj, Marc Thilo Figge

Cytometry A

2017-08-26

Streptococcus pneumoniae From Patients With Hemolytic Uremic Syndrome Binds Human Plasminogen via the Surface Protein PspC and Uses Plasmin to Damage Human Endothelial Cells

Christian Meinel*, Giuseppina Spartà, Hans-Martin Dahse, Franziska Hörhold, Rainer König, Martin Westermann, Sina M Coldewey, Zoltán Cseresnyés, Marc Thilo Figge, Sven Hammerschmidt, Christine Skerka, Peter F Zipfel#

The Journal of Infectuious Diseases