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A. fumigatus infection in virtual alveolus

In this project, a virtual infection with A. fumigatus in human or murine alveolus is simulated. The corresponding model considers…

Hyphal growth simulation

In this project, the growth of fungal hyphae is modeled. As a parameterized approach, different hyphal structures can be learned,…

JIPipe

ImageJ is a powerful tool for image analysis that is easy to learn and can be extended with hundreds of…

KITE

KITE (Kindergarten COVID-19 Test scenario evaluator) is a state-based model for simulating the spread of COID-19 in kindergartens. This software…

ODE/SBM Parameter Estimator

The ODE/SBM parameter estimator is a framework for simulating, estimating, and screening ordinary differential equations (ODEs) or state-based models (SBMs)…

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CellRain

CellRain is a C++ modelling framework for Monte-Carlo Simulations on microscopy images. It can be applied: to estimate microscopic parameters,…

Complement immune evasion of Candida albicans

The pH-regulated antigen 1 (Pra1) is a hierarchical complement inhibitor that is secreted by the fugal pathogen Candida albicans and…

Confrontation assay model

In this project a virtual confrontation assay of polymorphonuclear neutrophils (PMN) and Candida glabrata cell cluster is modelled. Bases on…

DeconvTest

For many existing deconvolution methods, it is challenging to choose the method and its parameters most appropriate for particular image…

Droplet analysis

Microfluidic droplet handling is an ultra-high throughput technique that allows for encapsulation of single microbes in isolated compartments to, for…

DynaCoSys

The DynaCoSys model combines respectively partial and ordinary differential equations for molecular concentrations in the fluid and on the surface,respectively.…

DynSPHARM

Spherical harmonics (SPHARM) expand a shape function on a sphere using a set of orthogonal spherical functions. This allows the…

Evolutionary Game Theory model

In evolutionary game theory a population of individuals, here A. fumigatus, is simulated. Under the pressure of the immune system…